I have opened an online shop where I’m selling all kinds of products with designs I've made from my photography.
If you haven't seen it on my Facebook or Instagram already, the link to my shop is curryosities.myspreadshop.com (or find it in the menu under Other Fun Stuff).
This shop is dedicated to my dearly departed mutt, Paughey. He was the most adorably dopey good dog and looks pretty good on a t-shirt! My nephews wear their Paughey shirts proudly with Parker making sure those who comment on it know “he’s dead”. Kids say the darndest things!
I'll be releasing new designs periodically and introducing them here! So keep checking back until you find something you like. Or, if there's something you're interested in, a specific product or animal, LET ME KNOW! I'll do my best to make it happen! I’ve already done several custom orders to rave reviews.
While this was intended to be an artistic outlet, it’s also a side hustle of sorts, so I do get a portion of the profits from your purchase. Help a girl working for a non-profit, living with her parents out.
This is a really niche post intended for geneticists who are doing de novo genome assemblies of 10X linked-reads sequencing data using Supernova (see… niche), but it also might be interesting to people who want to know a little bit about what the heck it is I do for a living.
A good amount of bioinformatics is Googling.
Supernova is an assembly program specifically for use with linked-reads sequencing data generated by 10X Genomics sequencing technology. Explaining exactly what linked-reads are can be a whole other post so if you want those details, go here. But for now, all you need to know is that it’s the raw data I am using to generate reference genomes from scratch (a.k.a. de novo).
The end product of a de novo assembly is something called a FASTA. This is a large file that contains all the As, Gs, Cs, and Ts in order for that genome. This file is what’s used to as a guide for doing future genomic analyses of the species.
In Supernova, there are 4 options for this output. The online documentation didn't go into enough depth on how the 4 output options work for me to really know which would be the best option for what we’re going to be using them for, and Googling didn’t get me any closer to an answer. So, I generated all 4 types of output, got assembly stats (QUAST & BUSCO) on all of them, and that gave me enough info to figure out which option would be best.
So, here's my very simplified takeaway from this endeavor:
Supernova represents sequences in the raw assembly as “microbubbles” and “megabubbles”.
It looks like a “bubble” is when there's more than one sequence assembled to a contig separated by "gaps" (single sequences or runs of Ns). Collections of microbubbles create megabubbles. These megabubbles then have to be flattened into a single sequence. This is where the output options come into play.
So, here’s the full breakdown that sounds like a riddle but isn’t a riddle:
raw is ALL the bubbles even microbubbles within megabubbles in one FASTA
megabubbles flattens microbubbles within megabubble arms in one FASTA
pseudohap flattens all the megabubbles to one FASTA
pseudohap2 is each flattened megabubble arm in a separate FASTA
I hope this helps some of my fellow Googling bioinfomagicians out there and didn’t make everyone else just super confused.
Find yourself a job that makes you well up with pride to be an employee every time you see new promotional material.
San Diego Zoo Wildlife Alliance participated in the 133rd Rose Parade for the first time in 25 years. The float’s design represents the interconnectedness of all life with a live action depiction of our new past, present, and future in wildlife conservation logo and a rotating globe with all our Hubs.
To bring all the efforts the San Diego Zoo does together as one cohesive team that strives to make the world better, the Zoological Society of San Diego turned San Diego Zoo Global is now the San Diego Zoo Wildlife Alliance!
This is more than just a sleek new logo and some new fonts. This change includes a restructuring of how we present ourselves and our work to the outside world. We want to make everything we do from animal care to research inside and outside of our facilities and across the world visible so you can share in the amazing stories that we live through every day.
We are so much more than just a Zoo and Safari Park. Sure, we have some remarkable places you can spend the day seeing some amazing animals, but we also have research and outreach happening across the globe aimed at improving the quality of life for all living things!
The biggest change for us researchers from the rebrand is the Institute for Conservation Research is no more. Though it was never the intension, having a separate entity within the organization for research made the science seem less accessible and inclusive. To more effectively bring the science to you, it is now just part of the San Diego Zoo Wildlife Alliance because the science isn't separate. We are one organization with a unified goal.
A Blue Moon is not just a beer. It's the second full moon in a month.
It's relatively rare, happening only about every two and a half years.
There is a full moon on Halloween every 19 years or so BUT not all time zones.
A full moon on Halloween for everyone? That hasn't happened since 1944*!
I hope you all had a chance to go outside to marvel in it's glory.
If not, here are some photos I took this evening.
*Disappointingly, this little bit of trivia makes Hocus Pocus inaccurate because there wasn't a full moon on Halloween in 1993, which was needed to bring the Sanderson Sisters back to life.
One All Hallows' Eve, when the moon is around
So, for the love of 2020, if you're a virgin, DO NOT LIGHT A BLACK CANDLE TONIGHT! Thank you.